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Updated: Jun 23, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
Plasmonic and Dielectric Metasurfaces for Enhanced Spectroscopic Techniques
Borja García García1,2, María Gabriela Fernández-Manteca1,2, Dimitrios C Zografopoulos3,4
1Photonics Engineering Group, Universidad de Cantabria, 39005 Santander, Spain.
Abstract:
Spectroscopic techniques such as Surface-Enhanced Raman Scattering (SERS), Surface-Enhanced Infrared Absorption (SEIRA), and Surface-Enhanced Fluorescence (SEF) are essential analytical techniques used to study the composition of materials by analyzing the way materials scatter light, absorb infrared radiation or emit fluorescence signals. This provides information about their molecular structure and properties. However, traditional SERS, SEIRA, and SEF techniques can be limited in sensitivity, resolution, and reproducibility, hindering their ability to detect and analyze trace amounts of substances or complex molecular structures. Metasurfaces, a class of engineered two-dimensional metamaterials with unique optical properties, have emerged as a promising tool to overcome these limitations and enhance spectroscopic techniques. This article provides a state-of-the-art overview of metasurfaces for enhanced SERS, SEIRA and SEF, covering their theoretical background, different types, advantages, disadvantages, and potential applications.
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