Related Experiment Video
Updated: Sep 13, 2025

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Murine Superficial Lymph Node Surgery
Published on: May 21, 2012
42.7K
Robot-Assisted Lymph Node-to-Vein Anastomosis: Lessons from the First 22 Cases at a High-Volume Lymphatic
Wei F Chen1, David C F Cheong1,2, Erica Tedone Clemente1
1Center for Lymphedema Research and Reconstruction, Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH 44124, USA.
Current Oncology (Toronto, Ont.)
|July 25, 2025
Summary
Robot-assisted lymph node-to-vein anastomosis (LNVA) is a safe and effective new procedure for lymphedema treatment. This robotic approach enhances precision and efficiency in supermicrosurgery, potentially improving outcomes for lymphatic and intracranial diseases.
Area of Science:
- Microsurgery
- Robotic Surgery
- Vascular Surgery
Background:
- Lymphedema is a frequent complication of cancer treatment.
- Supermicrosurgical techniques like lymphaticovenular anastomosis (LVA) and lymph node-to-vein anastomosis (LNVA) are effective for fluid-predominant lymphedema.
- Robotic assistance is a novel advancement in supermicrosurgery.
Purpose of the Study:
- To describe the initial experience with robot-assisted LNVA.
- To share technical insights and evaluate the feasibility of robotic supermicrosurgery.
- To explore the potential of robotics in extending surgical precision for lymphatic and intracranial diseases.
Main Methods:
- Twenty-two consecutive robotic LNVAs were performed by a high-volume supermicrosurgeon.
- Preoperative imaging (standard and ultra-high frequency ultrasound) guided lymph node and vein selection.
- The Symani Surgical System was utilized, with specific adaptations for enhanced motion scaling, ergonomics, and console control. Intraoperative patency was confirmed using direct washout and/or indocyanine green (ICG) transit.
Main Results:
- All 22 robotic LNVA procedures were technically successful, achieving 100% intraoperative patency.
- The average anastomosis time decreased significantly from 37 minutes to 18 minutes.
- Robotic assistance demonstrated improved precision, tremor elimination, and reduced technical difficulty at submillimeter scales.
Conclusions:
- Robot-assisted LNVA is a safe, feasible, and efficient procedure for lymphedema treatment.
- This robotic approach optimizes existing supermicrosurgical techniques.
- Robotic assistance has the potential to enable surgery at scales below 0.1 mm, expanding possibilities for lymphatic and intracranial conditions.

