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Related Experiment Video

Updated: Sep 13, 2025

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
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Optimizing Tumor Detection in Brain MRI with One-Class SVM and Convolutional Neural Network-Based Feature Extraction.

Azeddine Mjahad1, Alfredo Rosado-Muñoz1

  • 1GDDP, Department Electronic Engineering, School of Engineering, University of Valencia, 46100 Burjassot, Valencia, Spain.

Journal of Imaging
|July 25, 2025
PubMed
Summary
This summary is machine-generated.

This study developed AI methods for early brain tumor detection using magnetic resonance imaging (MRI). Deep learning models combined with One-Class Support Vector Machines (OCSVM) effectively identified anomalies in imbalanced datasets.

Keywords:
CNNsOCSVMbrain tumor detectiondimensionality reductionfeature-based methodsfrequency analysismedical imaging

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Area of Science:

  • Medical Imaging Analysis
  • Artificial Intelligence in Healthcare
  • Neuro-oncology

Background:

  • Early brain tumor detection is crucial for patient outcomes.
  • Medical imaging datasets often suffer from class imbalance, hindering traditional AI classification.
  • Developing robust AI for anomaly detection in scarce pathological data is a significant challenge.

Purpose of the Study:

  • To investigate the efficacy of One-Class Support Vector Machine (OCSVM) combined with deep learning feature extraction for brain tumor anomaly detection.
  • To compare the performance of various deep learning architectures (DenseNet121, VGG16, MobileNetV2, InceptionV3, ResNet50) and classical methods for feature extraction.
  • To evaluate a pure Convolutional Neural Network (CNN) approach for direct classification without OCSVM.

Main Methods:

  • Extracted features from healthy brain MRI images using deep learning architectures and classical techniques.
  • Trained a One-Class Support Vector Machine (OCSVM) exclusively on features from healthy brain images.
  • Compared the performance of hybrid CNN-OCSVM models against a pure CNN classification model.

Main Results:

  • Hybrid CNN-OCSVM models significantly improved anomaly detection over handcrafted features.
  • DenseNet121 (94.83% accuracy) and VGG16 (95.33% accuracy) showed strong performance in hybrid models.
  • A pure CNN model achieved superior accuracy (97.83%), demonstrating effective direct feature learning from MRI data.
  • MobileNetV2 offered a balance between accuracy and computational efficiency.

Conclusions:

  • AI models, particularly pure CNNs, can reliably detect brain tumor anomalies in imbalanced MRI datasets without pathological labels.
  • This approach offers a promising solution for clinical settings with limited abnormal samples.
  • Future work includes optimizing inference time, dataset expansion, and enhancing model explainability for clinical trust.