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Updated: May 31, 2026

Lensless On-chip Imaging of Cells Provides a New Tool for High-throughput Cell-Biology and Medical Diagnostics
Published on: December 14, 2009
ILViT: An Inception-Linear Attention-Based Lightweight Vision Transformer for Microscopic Cell Classification
Zhangda Liu1, Panpan Wu1, Ziping Zhao1
1College of Computer and Information Engineering, Tianjin Normal University, Tianjin 300387, China.
None:
Microscopic cell classification is a fundamental challenge in both clinical diagnosis and biological research. However, existing methods still struggle with the complexity and morphological diversity of cellular images, leading to limited accuracy or high computational costs. To overcome these constraints, we propose an efficient classification method that balances strong feature representation with a lightweight design. Specifically, an Inception-Linear Attention-based Lightweight Vision Transformer (ILViT) model is developed for microscopic cell classification. The ILViT integrates two innovative modules: Dynamic Inception Convolution (DIC) and Contrastive Omni-Kolmogorov Attention (COKA). DIC combines dynamic and Inception-style convolutions to replace large kernels with fewer parameters. COKA integrates Omni-Dimensional Dynamic Convolution (ODC), linear attention, and a Kolmogorov-Arnold Network(KAN) structure to enhance feature learning and model interpretability. With only 1.91 GFLOPs and 8.98 million parameters, ILViT achieves high efficiency. Extensive experiments on four public datasets are conducted to validate the effectiveness of the proposed method. It achieves an accuracy of 97.185% on BioMediTech dataset for classifying retinal pigment epithelial cells, 97.436% on ICPR-HEp-2 dataset for diagnosing autoimmune disorders via HEp-2 cell classification, 90.528% on Hematological Malignancy Bone Marrow Cytology Expert Annotation dataset for categorizing bone marrow cells, and 99.758% on a white blood cell dataset for distinguishing leukocyte subtypes. These results show that ILViT outperforms the state-of-the-art models in both accuracy and efficiency, demonstrating strong generalizability and practical potential for cell image classification.
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