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Related Concept Videos

Bioremediation00:46

Bioremediation

Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.
Sustainable Development01:43

Sustainable Development

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Environmental Applications of Microorganisms

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Microbial Wastewater Treatment

Microbial communities in aquatic ecosystems play a key role in the natural breakdown of contaminants introduced through domestic and industrial effluents. Acting as biological catalysts, these microbes change and mineralize a wide range of organic and inorganic pollutants under different redox conditions.In oxygen-rich surface waters, aerobic heterotrophs lead organic matter breakdown, using oxygen as the terminal electron acceptor to efficiently oxidize substrates to carbon dioxide and water.
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Related Experiment Video

Updated: Jun 13, 2026

An Additive Manufacturing Technique for the Facile and Rapid Fabrication of Hydrogel-based Micromachines with Magnetically Responsive Components
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Sustainable Hydrogels for Medical Applications: Biotechnological Innovations Supporting One Health.

Silvia Romano1,2, Sorur Yazdanpanah1,2, Orsolina Petillo1

  • 1Research Institute on Terrestrial Ecosystems (IRET)-CNR, Via Pietro Castellino 111, 80131 Naples, Italy.

Gels (Basel, Switzerland)
|July 25, 2025
PubMed
Summary

Sustainable, bio-based hydrogels derived from renewable resources offer promising solutions for regenerative medicine. These advanced biomaterials align with the One Health approach, enhancing human health while minimizing environmental impact.

Keywords:
One Healthbiocompatible polymersmicrobial fermentationrecombinant proteinssustainable hydrogels

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Sustainable Technologies

Background:

  • The One Health paradigm emphasizes interconnected health of humans, animals, and environment.
  • Bio-based hydrogels are emerging as key sustainable biomaterials for medical use.
  • These materials are produced using biotechnological methods from renewable resources.

Purpose of the Study:

  • To review the characteristics and medical applications of bio-based hydrogels.
  • To highlight their role in advancing sustainable healthcare solutions.
  • To discuss their potential within the One Health framework.

Main Methods:

  • Review of scientific literature on bio-based hydrogels.
  • Analysis of biotechnological production methods (genetic engineering, microbial fermentation).
  • Evaluation of material properties (biocompatibility, tunability, biodegradability).

Main Results:

  • Bio-based hydrogels are composed of renewable materials like collagen, elastin, silk fibroin, bacterial cellulose, xanthan gum, and hyaluronic acid.
  • Their properties make them suitable for wound healing, tissue regeneration, and ECM-mimicking scaffolds.
  • These hydrogels offer controlled mechanical properties and potential for minimally invasive administration.

Conclusions:

  • Sustainable, bio-based hydrogels are strategic innovations for regenerative medicine.
  • They align with the One Health approach by enhancing health and minimizing ecological impact.
  • These hydrogels represent a significant advancement in developing sustainable healthcare solutions.