Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Influence of Cycloplegia on Axial Length Prediction Models in a Paediatric Sample.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026

Same author

Influence of anterior chamber depth and vault on anterior chamber angle morphology after phakic posterior chamber intraocular lens implantation.

International ophthalmology·2024

Same author

Prediction model of the horizontal trabecular iris angle after phakic posterior chamber implantable intraocular lens surgery.

Journal of cataract and refractive surgery·2023

Same author

Repeatability and agreement of swept-source optical coherence tomography and partial coherence interferometry biometers in myopes.

Clinical & experimental optometry·2022

Same author

Vault differences in eyes implanted with spherical and toric implantable collamer lenses: an inter-eye analysis.

BMC ophthalmology·2022

Same author

Biometric and ICL-related risk factors associated to sub-optimal vaults in eyes implanted with implantable collamer lenses.

Eye and vision (London, England)·2021

Search research articles

Related Experiment Video

Updated: Sep 13, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Bilateral Simultaneous Full-Thickness Macular Holes: A Case Report with Spontaneous Resolution.

Isabel López-Bernal¹, Ángel Sánchez Trancón¹, Pedro Serra¹

¹Ophthalmology Clinic Vista Sánchez Trancón, 06010 Badajoz, Spain.

|July 25, 2025

Summary

Small macular holes (<250 µm) can close spontaneously, restoring vision. This case study supports a conservative, observational approach for select patients, potentially avoiding surgery for full-thickness macular holes.

Keywords:

bilateral macular hole optical coherence tomography spontaneous closure

More Related Videos

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Related Experiment Videos

Last Updated: Sep 13, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

Ophthalmology
Retinal Diseases

Background:

Full-thickness macular hole (FTMH) affects detailed vision, often idiopathic.
Small FTMH (<250 µm) may close spontaneously, but management is debated.
Surgical intervention is common for larger holes, but spontaneous closure occurs in ~25% of small holes.

Observation:

A 65-year-old female patient with bilateral FTMH was monitored via spectral domain optical coherence tomography (OCT).
Vitreomacular traction was identified as the cause of hole formation.
Spontaneous closure of both macular holes was observed, with associated visual acuity recovery.

Findings:

Spontaneous closure of small FTMH (<250 µm) is possible.
OCT imaging revealed bridging as the mechanism for spontaneous closure.
Visual acuity improved following spontaneous anatomical closure.

Implications:

This case supports a conservative, observational strategy for select small FTMH.
Non-surgical management may be appropriate, avoiding unnecessary interventions.
Understanding spontaneous closure mechanisms can guide clinical decision-making for macular hole treatment.