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Updated: Sep 13, 2025

Author Spotlight: Unraveling the Interplay Between Trichoderma stromaticum and the Mammalian Immune System
Published on: October 20, 2023
Trichophyton mentagrophytes genotype VII, an emerging infection: a Systematic Review
Luigi Cofone1, Lorenzo Paglione2, Fabiano Grassi1
1Department of Public Health & Infectious Diseases, Sapienza University of Rome, Italy.
Background:
In the past few years there has been a dramatic change in the prevalence of the genotype VII of the Trichophyton mentagrophytes. Trichophyton mentagrophytes is a dermatophyte fungus commonly found in wild, terrestrial and burrowing animals such as rabbits, that has now adapted to an anthropophilic environment and is responsible of an emerging zoonosis.
Study Design:
A thorough background research and a systematic review have been done to show the effect of this emerging dermatophytic infection on humans.
Methods:
Three electronic databases were searched for eligible studies: PubMed, Scopus and Web of Science. All the articles found were then screened, first, by title and abstract and, then, by full text. A quality assessment was done using the Newcastle-Ottawa Quality Assessment Scale (NOS).
Results:
28 articles were found. 4 of which were included in this review. These articles were produced in France, Switzerland, the USA and Germany. They showed interesting clinical evidence regarding how this inter-human multidrug resistant mycosis could easily become an epidemic sexually transmitted infection.
Conclusions:
This systematic review emphasizes how the spread of this pathogen, genotype VII, in humans must not be underestimated. Consequently, in order to facilitate early intervention and, thus, avoid a multi resistant epidemic growth of this infection, new diagnostic measures are required.
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