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Ecological Momentary Mobile Cognitive Screening for Cancer-Related Cognitive Impairment Among Patients With Lung
Mu-Hsing Ho1, Denise Shuk Ting Cheung, Jing-Yu Benjamin Tan
1Author Affiliations: School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong (Drs Ho, Cheung, and Lin), Pokfulam; and School of Nursing and Midwifery, University of Southern Queensland (Dr Tan), Ipswich, Australia.
Background:
Accessible, real-time cancer-related cognitive impairment (CRCI) assessments remain limited.
Objectives:
The aims of this study were to develop and validate the Single Item Mobile Cognitive Screening (SIM-Cog Screening) tool to detect CRCI, establish its concurrent validity and test-retest reliability, and assess feasibility through momentary assessments.
Methods:
A secondary analysis was conducted on data from 175 newly diagnosed patients with non-small cell lung cancer. Participants completed in-person assessments, including the Montreal Cognitive Assessment Hong Kong version 5-Min Protocol and Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) measures, and a mobile survey with SIM-Cog Screening and ratings of anxiety, depression, fatigue, pain, and sleep disturbance. A subgroup of 10 participants completed the ecological mobile survey twice daily for 7 days. Receiver operating characteristic curve analysis used the Montreal Cognitive Assessment Hong Kong version 5-Min Protocol and FACT-Cog measures as reference standards.
Results:
The receiver operating characteristic curve analysis revealed the area under the curve values of 0.928 when referenced against the FACT-Cog Perceived Cognitive Impairment-18. The optimal cutoff score of 4 on the FACT-Cog Perceived Cognitive Impairment-18 yielded a sensitivity of 88% and a specificity of 83.7%. Single Item Mobile Cognitive Screening scores correlated with measures of anxiety, depression, fatigue, and sleep disturbance. The test-retest reliability coefficient was 0.724, and participants reported high satisfaction with the ecological mobile survey.
Conclusions:
This brief, ecological mobile cognitive screening measure can transform how CRCI is detected, monitored, and managed, enabling timely interventions.
Implications For Practice:
Utilizing tools like SIM-Cog Screening can facilitate timely interventions tailored to individual patient needs, ultimately enhancing quality of life and treatment outcomes.
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