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Monoclonal Gammopathy in ANCA-Negative Pauci-Immune Crescentic GN: Is There an Association?

Maria J Vargas-Brochero1, Alessia Buglioni2, Poemlarp Mekraksakit1

  • 1Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.

Kidney360
|July 25, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
ANCAGNglomerular diseaseonco-nephrologyvasculitis

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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