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Updated: Sep 13, 2025

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
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Drug Repurposing Patent Applications October-December 2024
1H.M. Pharma Consultancy, Wien, Austria.
Assay and Drug Development Technologies
|July 25, 2025
Summary
Drug repurposing patent applications show diverse global innovation. Novel therapeutic uses were identified for conditions including Parkinson's disease, Angelman syndrome, and schizophrenia, highlighting significant advancements in late 2024.
Area of Science:
- Pharmaceutical Sciences
- Drug Discovery
- Intellectual Property
Background:
- Drug repurposing is a key strategy for developing new therapeutics.
- Recent patent filings indicate a surge in innovation in this field.
- Global interest in drug repurposing spans multiple continents and research institutions.
Purpose of the Study:
- To review significant PCT patent applications in drug repurposing published in late 2024.
- To highlight the diversity of applicants, therapeutic targets, and geographic representation.
- To showcase novel drug repurposing strategies and potential treatments.
Main Methods:
- Analysis of 17 PCT patent applications related to drug repurposing.
- Selection based on significance of innovation.
- Categorization by applicant, active agent, and geographic origin.
Main Results:
- Diverse applicants from US, China, Japan, Germany, UK, Canada, Algeria, and Iceland.
- Specific examples include entacapone for therapeutic hypothermia, sulindac for Angelman syndrome, and gliclazide for schizophrenia.
- Demonstrated potential for treating neurodevelopmental disorders and neurological conditions.
Conclusions:
- Late 2024 patent filings reveal a dynamic landscape of drug repurposing research.
- Innovation is geographically widespread, with significant contributions from various international entities.
- Identified repurposing candidates offer promising therapeutic avenues for challenging diseases.
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