Coronary Sinus Reducer Implantation in a Patient With Pre-Existing Left Ventricular Lead

Azhar Farooqui1, F Aaysha Cader1, Prashanth Raju1

  • 1Department of Cardiology, Kettering General Hospital, Kettering, United Kingdom.

JACC. Case Reports
|July 25, 2025
PubMed

Insights

Coronary sinus reducer (CSR) implantation is feasible in patients with existing left ventricular (LV) leads. However, potential challenges with future lead extraction and long-term device performance require further investigation.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • Coronary sinus reducer (CSR) implantation is a novel therapy for refractory angina.
  • Indications for cardiac resynchronization therapy (CRT) are expanding.
  • Safety data for CSR implantation in patients with prior left ventricular (LV) leads are limited.

Observation:

  • A case report details the successful implantation of a CSR device in a 79-year-old patient with ischemic cardiomyopathy and a pre-existing LV lead.
  • The patient presented with symptoms of refractory angina.

Findings:

  • CSR implantation in the presence of an LV lead is technically feasible.
  • Potential for LV lead trapping between the CSR stent and coronary sinus exists, potentially complicating future lead extraction.
  • Long-term effects of LV leads on CSR endothelialization and device failure rates are unknown.

Implications:

  • This case highlights the feasibility of CSR implantation in patients with prior LV leads.
  • Further research is needed to assess the long-term safety and efficacy of CSR in this patient population.
  • Consideration of potential lead-device interactions is crucial for procedural planning and patient management.
Abstract

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