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Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
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PediBIG: Optimizing the Brain Injury Guideline for Pediatric Care.
Jessica A Naiditch1, Karen Piper2, Elizabeth Tyler-Kabara1
1Dell Children's Medical Center of Central Texas, Austin, TX, USA; University of Texas - Austin Dell Medical School, Austin, TX, USA.
Journal of Pediatric Surgery
|July 27, 2025
Summary
Revising the Brain Injury Guideline (BIG) for pediatric traumatic brain injury may reduce hospital admissions. Moving non-displaced skull fractures to BIG 1 could prevent unnecessary consultations and hospitalizations.
Area of Science:
- Pediatric Traumatic Brain Injury
- Neurosurgical Consultation Guidelines
Background:
- High incidence of traumatic brain injury hospitalizations necessitates optimized care pathways.
- Improvements in medical technology may reduce the need for neurosurgical consultation in some pediatric TBI cases.
- The Brain Injury Guideline (BIG) was developed to mitigate unnecessary hospital admissions and consultations.
Purpose of the Study:
- To evaluate the existing pediatric Brain Injury Guideline (BIG).
- To identify patient and injury characteristics associated with hospitalization and neurosurgical consultation needs.
- To refine BIG criteria for pediatric traumatic brain injury management.
Main Methods:
- Retrospective cohort study of 10 years of data from a Level 1 Trauma Center.
- Analysis of 822 pediatric patients with traumatic brain injury.
- Logistic regression modeling to examine factors influencing neurosurgical consultation.
Main Results:
- Patients were categorized into BIG 1 (no admission/consult), BIG 2 (admission, no consult), and BIG 3 (admission and consult).
- In BIG 2, only 1 child required neurosurgical intervention, and 12 showed imaging progression.
- Non-displaced skull fractures were not statistically related to the need for neurosurgical intervention (p = 0.008).
Conclusions:
- Findings support the existing Brain Injury Guideline (BIG) for pediatric TBI.
- Reclassifying non-displaced skull fractures from BIG 2 to BIG 1 could reduce unwarranted hospital admissions.
- Optimizing the BIG may improve resource allocation and patient management in pediatric neurotrauma.

