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Updated: Jul 26, 2026

The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Spontaneous regression of "pauci-hemosiderotic" fibrolipomatous tumor
Alejandro Arbona-Lampaya1, Kumarasen Cooper2, Jenny T Bencardino3
1School of Medicine - University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico. alejandro.arbona@upr.edu.
Abstract:
A 64-year-old man presented with a palpable, soft, compressible, superficial mass on his left lateral hindfoot, with no other symptoms. No significant past medical history. Initial ultrasound and magnetic resonance imaging (MRI) studies characterized the mass as a cyst-like, fluid-containing lesion. Biopsy results indicated an atypical myxoid and spindle cell neoplasm, with immunohistochemistry favoring "pauci-hemosiderotic" fibrolipomatous tumor. Four months after the biopsy, follow-up MRI revealed substantial tumor size regression with decreased post contrast enhancement. Given the potential for recurrence and malignant transformation in hemosiderotic fibrolipomatous tumors, continuous monitoring and complete surgical excision are recommended.
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