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Updated: May 6, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Status Migrainosus - A Narrative Review.

Michellee Mayers1, Jerusalem Wogayehu2, Jessica Ailani2

  • 1Department of Neurology, Medstar Georgetown University Hospital, 3800 Reservoir Road NW PHC 7, 20007, Washington, D.C. , USA. Michellee.Mayers@medstar.net.

Current Neurology and Neuroscience Reports
|July 27, 2025
PubMed
Summary
This summary is machine-generated.

Status migrainosus (SM) is a severe migraine complication with high healthcare costs. Early treatment and preventative strategies are crucial for managing SM and preventing progression to chronic migraine.

Keywords:
ManagementMigraineMigraine attacksStatus migrainosus

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Area of Science:

  • Neurology
  • Clinical Medicine

Background:

  • Status migrainosus (SM) represents a significant challenge in migraine management.
  • Understanding its epidemiology, definition, and prognosis is crucial for effective patient care.

Purpose of the Study:

  • To review the current literature on status migrainosus.
  • To discuss its definition, epidemiology, management, and prognosis.

Main Methods:

  • Narrative review of existing scientific literature.
  • Synthesis of data on SM definition, prevalence, treatment, and outcomes.

Main Results:

  • SM incurs substantial healthcare costs due to high utilization rates.
  • Patients with SM experience increased emergency department visits, hospitalizations, and risk of chronic migraine.
  • Early intervention and preventative strategies are vital for SM management.
  • Diverse acute treatments and "bridge strategies" exist for refractory pain.
  • Physician identification and patient preparation are essential due to SM's debilitating nature.

Conclusions:

  • Effective management of SM requires early treatment and preventative measures.
  • Clinicians must educate patients about SM and develop proactive management plans.
  • Recognizing SM as a serious migraine complication is key to reducing disease burden.