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Updated: Sep 13, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
Bone Lesions of the Head and Neck
Nooshin K Dashti1, Darcy A Kerr1
1Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA; Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
None:
Head and neck bone tumors carry unique clinical, imaging, morphologic, and prognostic features compared to their peripheral counterparts and warrant a multidisciplinary approach for optimizing diagnosis and patient care. This review explores tumors characteristic of the head and neck (nasal chondromesenchymal hamartoma and osteochondromyxoma), as well as those that occur in other sites but have distinct features in this region (conventional and mesenchymal chondrosarcoma, osteosarcoma, and chordoma). Embryologic development and anatomic complexity of this region affect diagnostic considerations and patient management. Tumors involving the gnathic bones generally carry a better prognosis and those in the skull base a worse prognosis.
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