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Related Experiment Video

Updated: Jun 19, 2026

Conjunctival Commensal Isolation and Identification in Mice

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Feline Conjunctival Sequestra-A Case Series.

Carolina Cauduro da Rosa¹, Brett D Story², Sangwan Park²

¹Comparative Ophthalmology Laboratory, Federal University of Paraná, UFPR, Curitiba, Brazil.

Veterinary Ophthalmology

|July 28, 2025

Summary

This study describes feline conjunctival sequestra, a novel condition in cats. Histopathology revealed collagen compaction, similar to corneal sequestra, with possible links to chronic irritation or FHV-1 infection.

Keywords:

cat conjunctiva cornea necrosis sequestrum

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Area of Science:

Veterinary Ophthalmology
Feline Pathology

Background:

Corneal sequestrum is a known feline eye condition with unclear causes.
Conjunctival sequestrum has not been previously documented in cats.

Purpose of the Study:

To report the first series of cases of conjunctival sequestrum in cats.
To describe the clinical and histopathological features of this condition.

Main Methods:

A retrospective search of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database identified five cases.
Ophthalmological examination revealed black plaques in the conjunctiva.
Histopathology was performed on conjunctival and concurrent corneal lesions.

Main Results:

Conjunctival lesions showed focally extensive compaction and brunescence of proprial collagen without fibroblasts.
Three cases had overlying conjunctival ulceration.
The appearance was similar to feline corneal sequestra, with variable inflammation and microorganisms.

Conclusions:

This is the first case series documenting feline conjunctival sequestrum.
Concurrent ocular abnormalities were variable, preventing a definitive cause.
Chronic irritation and potential Feline Herpesvirus-1 (FHV-1) infection are suspected etiologies.