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Spontaneous Hemo-Mediastinum Following Laparoscopic Appendectomy: A Case Report
Abanoub Awad1, Isaac Theerman1, Jeremy F McBride2
1Department of Surgery, Mayo Clinic Health System, Eau Claire, WI, USA.
The American Journal of Case Reports
|July 28, 2025
Summary
This case report details a rare instance of spontaneous hemo-mediastinum following laparoscopic appendectomy. Early identification and intervention are crucial for managing this unusual complication.
Area of Science:
- Thoracic Surgery
- Interventional Radiology
- Gastrointestinal Surgery
Background:
- Hemo-mediastinum, or intra-thoracic bleeding, is rare, typically linked to trauma, malignancy, or spontaneous events.
- Spontaneous intra-thoracic bleeding post-laparoscopic appendectomy is exceptionally uncommon.
- This case involves a 65-year-old male with comorbidities presenting after an appendectomy.
Purpose of the Study:
- To report a unique case of spontaneous hemo-mediastinum after laparoscopic appendectomy.
- To emphasize the importance of prompt diagnosis and management of this rare complication.
Main Methods:
- A 65-year-old male underwent laparoscopic appendectomy for gangrenous appendicitis.
- Contrast-enhanced CT identified a mediastinal hematoma with active extravasation.
- Interventional radiology procedures included embolization of the bleeding vessel and bronchial artery.
- Surgical intervention involved thoracotomy for hematoma evacuation.
Main Results:
- The patient developed massive mediastinal hematoma and hemodynamic instability post-appendectomy.
- Initial interventional radiology embolization was followed by a second procedure for persistent hemoptysis.
- Surgical evacuation of the hematoma led to stabilization and recovery.
- This is the first reported case of post-appendectomy hemo-mediastinum.
Conclusions:
- Spontaneous hemo-mediastinum is an unusual complication of laparoscopic appendectomy.
- Timely and multidisciplinary intervention, including interventional radiology and surgery, is vital.
- This case underscores the need for vigilance in diagnosing rare post-operative complications.

