Interplay of miR-243 and microbial interactions in aging and transgenerational immunity
Arun Kumar1,2, Dilawar A Mir3, Mojibur R Khan1,4
1Molecular Biology and Microbial Biotechnology Laboratory, Division of Life Sciences, Institute of Advanced Study in Science and Technology (IASST), Guwahati, India.
None:
MicroRNAs (miRNAs) function in post-transcriptional regulation of gene expression and influence numerous biological processes. This commentary and view provide integrated insights from Kumar et al. (2024) and Gabaldon et al. (2020), emphasizing the role of miR-243 in promoting longevity and stress adaptation in response to microbial cues. However, further research is necessary to identify precise molecular targets of miR-243, comprehend its interactions with other miRNAs, validate its conservation in higher organisms, and to explore its potential toward targeted therapeutic strategies against aging and stress-related diseases.
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