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Updated: Jul 22, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Neuromodulation techniques in combination for a short-intensive treatment of depression and anxiety: a case report
Fiammetta Iannuzzo1, Federica Donia1, Lorenzo Bette1
1Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Via Consolare Valeria 1, Contesse, Messina 98125, Italy.
Abstract:
Neuromodulation techniques have emerged as valuable strategies for patients with depression and anxiety who do not respond to traditional therapies. Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) treatments are heterogeneous; however, they all share an average duration of at least 10 days, thus requiring significant patient commitment to maintain adequate compliance. Here we describe a 68-year-old woman who suffered from depression and generalized anxiety disorder and underwent a short-intensive combined protocol, thus highlighting its effectiveness and good tolerability.
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