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Updated: Sep 13, 2025
Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
Published on: April 18, 2013
Reversed halo sign on chest computed tomography: a retrospective analysis of 286 cases
Camila Soares Franco1,2, Paula Terra Martins Almeida Amaral3, Eduardo Kaiser Ururahy Nunes Fonseca1,3
1Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), São Paulo, SP, Brazil.
Objective:
To characterize the main causes of the reversed halo sign (RHS) on computed tomography (CT) of the chest and its imaging features.
Materials And Methods:
This was a retrospective study reviewing all chest CT scans for which the report contained the term "reversed halo sign" among those performed between 2015 and 2020 at a tertiary care hospital.
Results:
A total of 286 cases were identified, and the corresponding CT images and clinical data were reviewed. In this population, the most common cause of an RHS was pulmonary infarction (in 42%), followed by cryptogenic organizing pneumonia (in 17%) and bacterial pneumonia (in 16%). In addition, the CT characteristics of the RHS were identified in various conditions, such as pulmonary thromboembolism with pulmonary infarction, in which the RHS was typically smooth-walled and solitary with a peripheral distribution.
Conclusion:
The RHS can be observed in many contexts, and its CT characteristics, in combination with the clinical picture, can help narrow the differential diagnosis.
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