Related Experiment Video
Updated: Jun 28, 2026
11:17
Obtaining Highly Purified Toxoplasma gondii Oocysts by a Discontinuous Cesium Chloride Gradient
Published on: November 3, 2009
13.7K
Rhegmatogenous Retinal Detachment in Ocular Toxoplasmosis: A Case Series.
Sonny Caplash1, Manuel Paez Escamilla1, Sidra Zafar2
1Department of Ophthalmology, University of Pittsburgh, Pittsburgh, USA.
Cureus
|July 28, 2025
Summary
Ocular toxoplasmosis (OT) can lead to rhegmatogenous retinal detachment (RRD). Older age and inactive OT are risk factors. Surgical outcomes for RRD in OT patients show high re-attachment rates and potential visual improvement.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Retinal Surgery
Background:
- Ocular toxoplasmosis (OT) is a significant cause of posterior uveitis.
- Rhegmatogenous retinal detachment (RRD) is a potential complication of OT, impacting vision.
- Current management for RRD in OT lacks a standardized approach.
Observation:
- This case series reviewed six eyes (five patients) with OT-associated RRD.
- Patient age ranged from 27-77 years, with a predilection for those over 50.
- Retinal breaks were common, often superiorly located, with a high incidence of macula-off RRD.
Findings:
- Surgical intervention (pars plana vitrectomy with gas or scleral buckle with vitrectomy) resulted in 100% retinal re-attachment after one procedure.
- Four out of five surgically treated eyes experienced visual improvement.
- Risk factors identified include age over 50 and chronic or inactive acquired OT.
Implications:
- Age and inactive acquired OT are identified as risk factors for RRD in OT patients.
- Scleral buckle may be beneficial for specific tear locations or chronic RRD.
- Successful surgical management of RRD in OT is achievable, with good anatomical and visual outcomes.
