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Updated: Sep 13, 2025

Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry
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Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry

Published on: June 10, 2018

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Comonomer distribution analysis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)s using high-resolution MALDI-TOF

Naoki Kanayama1, Sayaka Nakamura1, Shin Sano2

  • 1Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan. n.kanayama@aist.go.jp.

Analytical Methods : Advancing Methods and Applications
|July 28, 2025
PubMed
Summary

Characterizing comonomer distribution in poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBH) is crucial for material properties. This study introduces a novel analytical method using MALDI-spiral-TOF-MS and Kendrick mass defect analysis to precisely determine PHBH comonomer distribution, even in biodegraded samples.

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