Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Protein Organization

Protein Organization

Protein Folding

Protein Folding

Ionic Crystal Structures

Ionic Crystal Structures

Ionic crystals consist of two or more different kinds of ions that usually have different sizes. The packing of these ions into a crystal structure is more complex than the packing of metal atoms that are the same size.
Most monatomic ions behave as charged spheres, and their attraction for ions of opposite charge is the same in every direction. Consequently, stable structures for ionic compounds result (1) when ions of one charge are surrounded by as many ions as possible of the opposite...

Protein and Protein Structure

Protein and Protein Structure

Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

High Pressure Synthesis of Ultrasmall Nanodiamonds with Nitrogen Vacancy Centers.

Nano letters·2026

Same author

Supportive parenting moderates the link between parents' and children's internalizing symptoms in families of color.

Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)·2026

Same author

Staging and defect-limited intercalation of FeCl<sub>3</sub> in graphite electrodes.

Nature communications·2026

Same author

Toward Hydrogen Isotope Separations through Strong Hydrogen Adsorption at Open Copper(I) Sites in an Ultramicroporous Metal-Organic Framework.

Journal of the American Chemical Society·2026

Same author

Engineering <i>Escherichia coli</i> for Urease-Driven Synthesis of Metal Oxide Nanomaterials.

ACS synthetic biology·2026

Same author

Synthetic Control over the Electron-Beam Stability of Upconverting Nanoparticles.

Nano letters·2026

Same journal

Correction to "Ultrasonication-Triggered Ubiquitous Assembly of Magnetic Janus Amphiphilic Nanoparticles in Cancer Theranostic Applications".

Nano letters·2026

Same journal

Tunable Proximity Valley Splitting Via Interfacial Exchange Pinning in WSe<sub>2</sub>-CrBr<sub>3</sub>-CrPS<sub>4</sub> Heterostructures.

Nano letters·2026

Same journal

Nanoscale Organization of Membrane Tension during Neutrophil Extracellular Trap Formation Revealed by Fluorescence Lifetime Imaging.

Nano letters·2026

Same journal

Pressure-Tuned Plasmonic Propagation on a Silver Nanowire.

Nano letters·2026

Same journal

Intrinsic Superconducting Gap in Bilayer KCa<sub>2</sub>Fe<sub>4</sub>As<sub>4</sub>F<sub>2</sub> and Decoupled Monolayer FeAs.

Nano letters·2026

Same journal

Programmable Hydrogen-Assisted Chemical Vapor Deposition Growth and Bipolar Transport in Two-Dimensional MoO<sub>2</sub> Nanoflakes.

Nano letters·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Sep 13, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Three-Dimensional Crystals Assembled by Linear Oligopeptoids.

Yen Jea Lee¹, Peter Ercius², Xubo Luo¹

¹Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.

|July 28, 2025

Summary

This summary is machine-generated.

Researchers designed three-dimensional (3D) peptoid crystals from short polymers. Precise control over polymer chain ends enabled the growth of thick, crystalline lamellae, overcoming challenges in 3D crystal formation.

Keywords:

3D crystal 4D-STEM peptoid self-assembly terminus

More Related Videos

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

Related Experiment Videos

Last Updated: Sep 13, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

Area of Science:

Polymer Chemistry
Materials Science
Crystallography

Background:

Constructing three-dimensional (3D) crystalline lattices from synthetic polymers is challenging due to limited driving forces for isotropic growth.
Short-chain polymers typically form two-dimensional (2D) crystalline structures like nanosheets.

Purpose of the Study:

To design and create 3D peptoid crystals from linear peptoid hexamers.
To overcome limitations in achieving 3D crystal growth from synthetic oligomers.

Main Methods:

Utilized amphiphilic diblock sequences to create linear peptoid hexamers.
Modified chain termini and removed amorphous domains to promote crystal growth.
Analyzed crystal structure and lattice parameters.

Main Results:

Achieved formation of crystalline lamellae up to 500 nm thick, significantly exceeding typical 2D nanosheet dimensions.
Observed stacking of unit cells with lattice parameters comparable to 2D nanosheets.
Identified compact C-terminal moieties as crucial for facilitating vertical growth and enhancing crystallinity.

Conclusions:

Demonstrated the successful rational construction of 3D peptoid crystals.
Highlighted the critical role of atomic precision in terminus chemistry for achieving long-range ordering and isotropic crystal growth.
Opened new avenues for designing macroscale crystals from oligomeric peptoids.