Advantages of Hao's esophagogastrostomy by fissure technique: study protocol for a prospective clinical trial

In the past, total gastrectomy (TG) was the most common surgical method, but now proximal gastrectomy (PG) has gradually become an alternative surgical method for proximal gastric and esophagogastric junction cancer. However, there is no recognized preferred anastomosis method after PG. In view of this, Hao's esophagogastrostomy by fissure technique (HEFT) proposed by the author's team can reduce the difficulty of the operation and the occurrence of postoperative complications. 13 cases that underwent this technique were free of complications during postoperative follow-up, and the intraoperative anastomosis time was significantly shorter than that reported in the literature for Double-flap technique (45 min vs. 79-114 min).

This is a single-center, single-arm, prospective clinical study. We will recruit 30 eligible patients consecutively to undergo HEFT. The primary objective is to assess perioperative safety. The secondary objectives: (1) Incidence of postoperative reflux esophagitis and anastomotic stenosis; (2) Assess the quality of life at 3 Months Postoperatively by EORTC QLQ-C30 and EORTC QLQ-STO22 scales. Measurement data will be presented as mean ± standard deviation ($\overline{x}\hspace{0.17em}\pm \text{\hspace{0.17em}s}$). Count data will be presented as rates (%).