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Updated: Sep 13, 2025
Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
Published on: March 29, 2022
Profile of peripheral refraction, choroidal thickness, and its correlation with refraction among children with myopia
Anusha Paritala1,2,3, Janarthanam Jothi Balaji3, Aparna Gopalakrishnan3
1Elite School of Optometry, Unit of Medical Research Foundation, Chennai, Tamil Nadu, India.
Insights
Indian children with myopia show hyperopic relative peripheral refraction and choroidal thinning towards the periphery. These two factors, relative peripheral refraction and choroidal thickness, are positively correlated in pediatric myopia.
Area of Science:
- Ophthalmology
- Optometry
- Pediatric Eye Care
Background:
- Myopia progression is linked to relative peripheral refraction (RPR) and choroidal thickness (ChT).
- Limited data exists on RPR and ChT distribution in Indian children.
Purpose of the Study:
- To investigate the distribution of RPR and ChT in Indian myopic children.
- To explore the relationship between RPR and ChT in this population.
Main Methods:
- Prospective cross-sectional study of 58 myopic children (ages 6-12).
- Assessed axial length, RPR, and ChT up to 20° nasal and temporal eccentricities.
- Utilized ARGOS, WAM-5500, and OCT-1 for measurements.
Main Results:
- Mean hyperopic RPR observed at 20° nasal (+0.30 ± 1.36 D) and temporal (+1.24 ± 1.52 D) eccentricities.
- Significant difference in RPR between nasal and temporal eccentricities, with temporal showing higher hyperopia.
- Choroidal thickness thinned from center to periphery (270.18 µm to 213.04 µm temporally and 136.78 µm nasally).
- Positive correlation found between peripheral refraction and peripheral ChT.
Conclusions:
- Indian myopic children exhibit hyperopic RPR and peripheral choroidal thinning.
- A positive relationship exists between RPR and ChT in the periphery of myopic children.
Purpose:
Relative peripheral refraction (RPR) and choroidal thickness (ChT) are two of the important components associated with the progression of myopia. There is a paucity of knowledge on the distribution profile of these components among Indian children.
Methods:
This is a prospective cross-sectional study involving 58 participants of age group 6-12 years. Axial length (ARGOS, Suntec, Inc., Aichi, Japan), peripheral refraction (WAM-5500, Grand Seiko CO. LTD., Hiroshima, Japan), and ChT (Deep Range Imaging, OCT-1, Atlantis, Topcon, Tokyo, Japan) of myopic children (-1.00 to -6.00 D) were assessed. Both RPR and ChT were assessed up to 20° at nasal and temporal eccentricities.
Results:
The RPR showed mean hyperopia at both nasal and temporal 20° eccentricities (mean ± SD; 20° nasal: +0.30 ± 1.36 D; temporal 20°: +1.24 ± 1.52 D), and the difference in refraction was significant with temporal 20° showing higher hyperopic refraction compared to nasal 20° (-0.94 ± 1.94 D, P < 0.01). Thinning of the choroid was observed from center to periphery at temporal 20°: 213.04 ± 65.22 µm and nasal 20°: 136.78 ± 37.46 µm eccentricities compared to the sub-foveal ChT 270.18 ± 67.10 µm. A positive correlation between the peripheral refraction and peripheral ChT was observed.
Conclusion:
Indian myopic children had hyperopic RPR along the horizontal meridian and thinning of the choroid from the center (SFCT) to the periphery. There is a positive relation between these two parameters.
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