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Peripheral biomarkers in compulsive sexual behavior disorder: a systematic review
Bianca de O Ferreira1, Bruno J Teixeira2, Leda L Talib3
1Experimental Pathophysiology Post-Graduation Program, Faculdade de Medicina, Universidade de São Paulo, 01246-903, São Paulo, SP, Brazil.
Sexual Medicine Reviews
|July 28, 2025
Summary
This review found peripheral biomarkers in compulsive sexual behavior disorder (CSBD) linked to stress, hormones, and inflammation. Further research is needed to understand their clinical use.
Area of Science:
- Neurobiology
- Biochemistry
- Psychiatry
Background:
- Compulsive sexual behavior disorder (CSBD) is a recognized condition characterized by impaired impulse control, causing significant distress.
- The neurobiological underpinnings of CSBD remain largely unclear.
- Understanding peripheral biomarkers may offer insights into CSBD's biological mechanisms.
Conclusions:
- Preliminary evidence suggests a multifactorial biological profile in CSBD involving stress, hormonal, and inflammatory pathways.
- Current findings indicate potential biological alterations but have limited clinical applicability.
- Future longitudinal studies in diverse populations are crucial to establish the diagnostic and clinical relevance of these peripheral biomarkers.
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