Related Experiment Video
Updated: Sep 13, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Smooth predictions for age-period-cohort models: a comparison between splines and random process
Connor Gascoigne1, Andrea Riebler2, Theresa Smith3
1MRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Medicine, Imperial College London, London, UK. c.gascoigne@imperial.ac.uk.
Background:
Age-Period-Cohort (APC) models are well used in the context of modelling health and demographic data to produce smooth predictions of each time trend. When producing smooth predictions in the context of APC models, there are two main schools, frequentist using penalised splines, and Bayesian using random processes with little crossover between them.
Methods:
We compared prediction using APC models in either a frequentist or Bayesian paradigm using theory, simulated data, and two separate real-world data examples for mental ill-health outcomes. For the theoretical comparison, we describe each method and give an accessible description highlighting how the two methods are equivalent. For the simulated and real-world data, we compared the results for both in-sample (estimation) and out-of-sample (forecasting) prediction.
Results:
During the simulation study, the estimation results for both the penalised splines and random processes were almost identical. For the forecasting results, the random processes performed better. For the real-world examples, the estimation results for both were extremely close with random processes proving slightly better. For the real-world data forecasting results, the random processes provided a significant improvement over penalised splines.
Conclusions:
The combination of theory and data examples we presented here make the relationship between splines and random processes both accessible and interpretable. Whilst there is a theoretical link between both penalised splines and random processes, when forecasting is the goal, a Bayesian random process approach displayed better predictive properties in comparison to the frequentist penalised spline approach.
More Related Videos
04:35Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
Published on: July 3, 2020
07:13Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
Published on: April 18, 2025
Related Concept Videos
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Assumptions of Survival Analysis
Mechanistic Models: Compartment Models in Individual and Population Analysis
Comparing the Survival Analysis of Two or More Groups
Introduction To Survival Analysis
The primary goal of survival analysis is to estimate survival time—the time...
Residuals and Least-Squares Property
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...