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Efficacy of manual therapy for cervical vertigo: a randomized controlled trial protocol
Chao Lu1,2, Jie Chen3,4, Feng Gao1
1Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210029, Jiangsu Province, China.
Journal of Orthopaedic Surgery and Research
|July 28, 2025
Summary
This study investigates synergistic manual therapy for cervical vertigo (CV). It compares this whole-spine approach to local cervical manual therapy and a waiting list, aiming to improve treatment options for CV patients.
Area of Science:
- Integrative and Complementary Medicine
- Neurology
- Musculoskeletal Medicine
Background:
- Cervical vertigo (CV) is common, but effective treatments are scarce.
- Manual therapy shows promise for CV, yet evidence quality is low.
- Current manual therapies often neglect a whole-spine approach, focusing only on the cervical spine.
Purpose of the Study:
- To evaluate the short-term effectiveness of synergistic manual therapy (SM) for cervical vertigo.
- To compare SM therapy against local cervical manual therapy (CM) and a waiting list (WL) control group.
- To provide a rigorous assessment of a novel, comprehensive manual therapy approach for CV.
Main Methods:
- A randomized controlled trial (RCT) involving 138 patients.
- Participants allocated to SM, CM, or WL groups for 2 weeks, with a 3-month follow-up.
- Primary outcome: change in vertigo intensity (Dizziness Handicap Inventory); Secondary outcomes: blood flow velocity, spinal scores, quality of life, adverse events.
Main Results:
- Results are pending as this is a study design abstract.
- The primary outcome measure is the Dizziness Handicap Inventory (DHI) to assess vertigo intensity changes.
- Secondary outcome measures include vertebrobasilar artery blood flow velocity, cervical spine scores, and health-related quality of life.
Conclusions:
- This RCT is the first rigorous study to compare synergistic manual therapy (SM) with local cervical manual therapy (CM) and no treatment for CV.
- Findings will offer an objective clinical basis for utilizing SM therapy in managing cervical vertigo.
- The study aims to enhance treatment strategies for patients suffering from cervical vertigo.

