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Epistaxis01:30

Epistaxis

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
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Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

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Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
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Suctioning the Nasopharyngeal Airway01:29

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Endotracheal Intubation I: Procedure01:15

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Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
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Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

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Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
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Administering Oxygen by Nasal Cannula01:29

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Related Experiment Video

Updated: Sep 13, 2025

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA
04:56

Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA

Published on: July 14, 2023

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Nasal Injuries Related to Respiratory Support Interfaces in Preterm Infants: Neonatal Course and 12-Month Outcome.

Marielle Jamaux1, Corisande Gibier1, Laurence Dillenseger1

  • 1Médecine et Réanimation du Nouveau-né, Service de Pédiatrie 2, Pôle Médico-Chirurgical Pédiatrique Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Avenue Molière, 67098 Strasbourg, France.

Children (Basel, Switzerland)
|July 29, 2025
PubMed
Summary

Nasal injuries are common in preterm infants needing respiratory support, often caused by ventilation devices. Over half of these injuries lead to lasting skin issues, impacting infant well-being.

Keywords:
continuous positive airway pressurenasal injurynon-invasive ventilationpreterm infantsrespiratory supportskin injury

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Area of Science:

  • Neonatology
  • Pediatric Dermatology
  • Medical Device Technology

Background:

  • Preterm infants' delicate skin is vulnerable to breakdown from respiratory support devices.
  • Nasal injuries are a significant concern in neonates requiring mechanical ventilation.
  • Immature skin integrity in premature infants increases risk of injury from medical equipment.

Purpose of the Study:

  • To investigate the incidence and severity of nasal injuries in preterm infants due to respiratory support.
  • To evaluate the short-term and medium-term sequelae of these nasal injuries.
  • To identify factors associated with the development and outcome of respiratory support-related nasal injuries.

Main Methods:

  • Prospective observational study of preterm infants (<33 weeks gestational age) with nasal injuries.
  • Utilized a validated scale to record injury severity at multiple time points (inclusion, 3, 7, 28 days).
  • Assessed sequelae at discharge and at 4, 9, and 12 months post-menstrual age.

Main Results:

  • 23% of infants (64/276) developed nasal injuries, primarily stage 1 or 2.
  • Continuous positive airway pressure (CPAP) was the most frequent interface associated with injury (83%).
  • 59% of infants showed sequelae at discharge, with 66% experiencing esthetic sequelae at 12 months.

Conclusions:

  • Nasal injuries are frequent complications of respiratory support in preterm infants.
  • A significant proportion of infants experience medium-term sequelae, including scarring and esthetic changes.
  • Injury site and type of respiratory support influence injury evolution and outcomes.