Related Experiment Video
Updated: Sep 13, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Current Trends in Clinical Trials for Merkel Cell Carcinoma (MCC)
Tilak Patel1, Rachel Butz2, Brian Boulmay1
1Division of Hematology and Oncology, Department of Medicine, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA 70112, USA.
Merkel cell carcinoma (MCC), a rare skin cancer, is aggressive and often recurs. Current clinical trials are exploring new treatments like immunotherapies and combination therapies to improve patient outcomes.
Area of Science:
- Oncology
- Dermatology
- Cancer Research
Background:
- Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer.
- MCC is characterized by high rates of recurrence and metastasis.
- Traditional treatments include surgery, radiation, and chemotherapy.
Discussion:
- Current clinical trials are investigating novel therapeutic strategies for MCC.
- Emerging treatments include immunotherapies, intratumoral injections, and combination therapies.
- These trials aim to overcome the limitations of conventional MCC management.
Key Insights:
- The review highlights recent advances in the clinical management of MCC.
- Investigational therapies show promise in improving outcomes for this rare cancer.
- Focus is shifting towards targeted and immune-based approaches.
Outlook:
- Further research and clinical trials are crucial for advancing MCC treatment.
- Combination therapies may offer synergistic benefits in managing advanced MCC.
- Improved therapeutic strategies are expected to enhance survival rates and quality of life for MCC patients.
More Related Videos
07:42Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients
Published on: February 7, 2021
09:29Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
Published on: September 30, 2016
Related Concept Videos
Targeted Cancer Therapies
There are several types of targeted therapies against...
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Mitogens and the Cell Cycle
Treatment Resistant Cancers
Tumor Immunotherapy