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Optimization of Extraction Parameters for Phenolics Recovery from Avocado Peels Using Ultrasound and Microwave
Lorena Martínez-Zamora1,2, María Carmen Bueso3, Mathieu Kessler3
1Postharvest and Refrigeration Group, Department of Agricultural Engineering & Institute of Plant Biotechnology, Universidad Politécnica de Cartagena, 30203 Cartagena, Murcia, Spain.
Foods (Basel, Switzerland)
|July 29, 2025
Summary
Ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE) efficiently recover bioactive compounds from avocado peels. UAE demonstrated superior efficiency for procyanidin extraction, highlighting its potential for sustainable agri-food practices.
Area of Science:
- Food Chemistry
- Green Chemistry
- Biotechnology
Background:
- Avocado peels (Persea americana) represent a significant waste stream (~20% of fruit weight).
- These peels are rich in valuable bioactive compounds with high revalorization potential.
- Valorizing avocado waste can contribute to a more sustainable agri-food sector.
Purpose of the Study:
- To optimize phenolic compound extraction from avocado peels using ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE).
- To compare the efficiency of UAE and MAE in extracting total antioxidant capacity (TAC) and total phenolic compounds (TPC).
- To identify optimal extraction parameters for maximizing phenolic recovery.
Main Methods:
- Central Composite Design (CCD) was employed to optimize extraction parameters.
- Variables studied included ethanol (EtOH) concentration, temperature, and time for both UAE and MAE.
- Phenolic content and antioxidant capacity were quantified; individual phenolics were analyzed using HPLC/MS.
Main Results:
- Ethanol concentration emerged as the most critical factor influencing phenolic extraction.
- Optimal conditions were identified as 94.55% EtOH with moderate temperatures and short extraction times.
- UAE showed superior performance, extracting 15% more procyanidins under milder conditions (45 °C for 5 min) compared to MAE (67 °C for 12 min).
Conclusions:
- Both UAE and MAE are effective technologies for extracting antioxidants from avocado peels.
- UAE offers a more efficient and potentially greener alternative due to lower temperature and time requirements.
- The findings support the sustainable valorization of avocado processing byproducts.

