[Renal and nephronal function diagnosis in the aged experimental rat]

An investigation method concerning the renal and nephronal functional diagnostics on the experimental animal rat without analysis of microbes, without micropuncture technique and without use of inulin or paraamino-hippuric acid-analogous radiopharmaca is demonstrated. It is based on the steady state investigation principle using inulin and paraamino-hippuric acid as test substances. The exactness of the method is established by critical considerations of the methods concerning the stabilisation of the humoral balance. by estimation of the behaviour of the functional parameters after heminephrectomy as well as by comparative valuation of the own results by findings reported in literature. The established renal and nephronal functional parameters comprise glomerulofiltrative and tubulosecretory as well as tubuloreabsorptive processes in the water, sodium and paraamino-hippuric acid treatment.