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Related Concept Videos

Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

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Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
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Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

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Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
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Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

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Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
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Related Experiment Video

Updated: Sep 13, 2025

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
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Combining Laboratory and Imaging Evaluation for Cardiovascular Risk Stratification in Systemic Lupus Erythematosus.

Chrysanthi Staveri1, Vassiliki Vartela2, Sophie I Mavrogeni3

  • 1Division of Rheumatology, Department of Internal Medicine, Patras University Hospital, GR 26504 Patras, Greece.

Journal of Clinical Medicine
|July 29, 2025
PubMed
Summary

Systemic lupus erythematosus (SLE) patients face higher cardiovascular disease (CVD) risks. Identifying SLE-specific factors can help create algorithms for early CVD risk detection and management in these patients.

Keywords:
auto-antibodiescardiovascular riskgenetic factorsmagnetic resonance imagingsystemic lupus erythematosus

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Area of Science:

  • Rheumatology and Immunology
  • Cardiovascular Medicine

Background:

  • Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organs, including the cardiovascular system.
  • SLE patients, predominantly young women, exhibit an elevated risk of cardiovascular disease (CVD).
  • Traditional CVD risk factors alone may not fully capture the heightened risk in SLE.

Purpose of the Study:

  • To review SLE-specific factors for early identification of cardiovascular risk.
  • To explore the potential of developing an algorithm for CVD risk stratification in SLE patients.

Main Methods:

  • Review of existing literature on SLE and cardiovascular disease.
  • Identification of SLE-related indices beyond traditional risk factors.
  • Discussion of imaging parameters, auto-antibodies, disease manifestations, medications, and genetic factors.

Main Results:

  • SLE is associated with increased CVD risk, even in young patients.
  • SLE-specific factors offer valuable insights into CVD risk stratification.
  • A combination of traditional and SLE-specific factors can inform risk assessment.

Conclusions:

  • Early identification of CVD risk in SLE patients is crucial.
  • Utilizing SLE-specific indices can aid in developing predictive algorithms.
  • Timely intervention can reduce CVD-related morbidity and mortality in SLE, improving quality of life.