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Association between Systemic Immune-Inflammation Index (SII) and secondary haemorrhage risk after tonsillectomy
Murat Gümüşsoy1, Özlem Yagız Agayarov1, İbrahim Çukurova1
1Department of Otolaryngology Head and Neck Surgery, University of Health Sciences, Izmir Tepecik Training and Research Hospital, Izmir, Turkey.
Objectives:
This study evaluates the relationship between Systemic Immune-Inflammation Index and secondary tonsillar haemorrhage after tonsillectomy.
Methods:
Sixty pediatric patients with secondary haemorrhage and 60 without bleeding were grouped for comparative analysis. Laboratory parameters and Systemic Immune-Inflammation Index values were collected preoperatively, on the bleeding day and on the control day, then compared.
Results:
Secondary haemorrhage occurred in 60 patients (3.11 per cent), with a mean age of 8.85 ± 3.07 years. Bleeding occurred at 8.63 ± 2.32 days post-operatively (range: 72 hours-21 days). Tonsillectomy day: Neutrophil count and Systemic Immune-Inflammation Index were significantly higher in the haemorrhage group (p < 0.001). Haemorrhage vs. tonsillectomy day (haemorrhage group): Platelet, neutrophil and Systemic Immune-Inflammation Index increased, while lymphocytes decreased (p < 0.001). Haemorrhage vs. control day: Neutrophil count and Systemic Immune-Inflammation Index remained significantly higher (p < 0.001).
Conclusion:
Systemic Immune-Inflammation Index, a novel inflammatory marker, may help predict post-tonsillectomy haemorrhage risk.
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