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Melanocytes in odontogenic keratocyst
Acta Pathologica Japonica
|July 1, 1985
Summary
Melanocytes were found in the basal layer of odontogenic keratocyst (OKC) epithelium in 10.6% of cases. Further research is needed to determine the origin of these melanocytes in OKC.
Area of Science:
- Oral pathology
- Dermatology
- Histopathology
Background:
- Odontogenic keratocyst (OKC) is a common developmental cyst of the jaw.
- The presence and origin of melanocytes within OKC epithelium are not well-understood.
Purpose of the Study:
- To investigate the presence and prevalence of melanocytes in the epithelial lining of odontogenic keratocysts.
- To discuss the potential histogenesis of melanocytes in OKC.
Main Methods:
- Histopathological examination of 47 odontogenic keratocyst (OKC) tissue samples.
- Identification and localization of melanocytes within the basal layer of the cyst's lining epithelium.
Main Results:
- Melanocytes were identified in the basal layer of the lining epithelium in 5 out of 47 (10.6%) OKC cases.
- The distribution and density of these melanocytes were noted.
Conclusions:
- Melanocytes are present in a subset of odontogenic keratocysts.
- The origin of melanocytes in OKC requires further investigation, with possible histogenetic pathways to be explored.