Related Experiment Video
Updated: Sep 13, 2025

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Patient-Identified Barriers to Hepatitis C Treatment
Joey Buytendorp1, Serena Xiong1, Darin Brink1
1Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN.
Introduction:
Hepatitis C virus (HCV) remains a public health concern in the United States. We developed a quality improvement project to address persistent challenges to HCV treatment at one primary care clinic. Challenges addressed included barriers to accessing specialist care to receive antiviral treatment and lack of patient resources, education, and awareness. Recognizing the potential for primary care providers to bridge treatment gaps, our initiative at an urban family medicine residency clinic in a large Midwest city targeted a patient population diagnosed with HCV but who remained untreated.
Methods:
Searching the medical record, we identified 40 eligible patients who had not received treatment despite a positive HCV diagnosis. Enrolled participants were asked to report their awareness, perceived barriers, and willingness to receive treatment in a primary care setting via a phone-assisted survey.
Results:
A total of 16 patients completed the survey (response rate 40%). Eighty-two percent were aware of their diagnosis, and 68.8% had not completed treatment. Only seven (43.8%) understood what an HCV infection is, while eight (50.0%) were aware that untreated HCV can lead to liver damage and cancer. Six (37.5%) claimed not to understand what an HCV infection is, and five reported that a medical professional had never explained it to them. Most respondents (81.2%) expressed a desire to initiate a treatment regimen and preferred to receive treatment at their primary care clinic.
Conclusion:
In an urban primary care residency clinic, HCV treatment is both possible and desired by patients.
More Related Videos
11:34A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
Published on: May 10, 2022
07:25Author Spotlight: Investigating Liver Cancer Pathogenesis Using Patient-Derived Organoids
Published on: August 18, 2023
Related Concept Videos
Barriers to Effective Communication II
Cultural barriers:
Differences in values, beliefs, religion, knowledge, and tradition can significantly impact communication. Awareness of nonverbal cues is critical, especially when conversing with a patient from a different culture. What appears appropriate in one culture may be inappropriate in another.
Semantic barriers:
As a result of their tendency to use...
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Factors Affecting Protein-Drug Binding: Patient-Related Factors
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...