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Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics
Published on: January 8, 2018
Harnessing Imaging Across Medical Specialties: Present Value and Future Radiomic Horizons
1Department of Radiologic, Oncologic and Anatomo-Pathologic Sciences, Sapienza University, Rome, Italy.
Abstract:
Diagnostic imaging plays a pivotal role across all medical disciplines, serving as the cornerstone for decision-making in both acute and chronic care. This article explores emerging evidence from diverse specialties-ranging from ophthalmology and hepatology to neurology and respiratory medicine-highlighting the indispensable role of imaging in guiding pharmacological, surgical, and rehabilitative strategies. More importantly, it emphasizes the transformative potential of radiomics, a data-driven approach that extracts high-dimensional quantitative features from routine CT, MRI, PET, and ultrasound scans. Unlike traditional qualitative interpretation, radiomics enables the development of predictive models that integrate imaging biomarkers with clinical, molecular, and genomic data. Case examples illustrate how radiomic analysis can improve disease stratification, guide perso-nalized therapies, and accelerate clinical trials. By leveraging existing picture-archiving systems without requiring additional procedures or contrast agents, radiomics offers a non-invasive "virtual biopsy" that expands the informational yield of every scan. This paradigm shift toward image-based precision medicine will require interdisciplinary collaboration between radiologists, clinicians, and data scientists but holds the promise of more accurate, efficient, and individualized care. The convergence of radiomic analytics and multidisciplinary practice heralds a new era in which imaging becomes not just a diagnostic tool, but a rich and reusable data asset that shapes therapeutic decisions and health outcomes.
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