[Hidradenitis suppurativa; a condition with multiple phenotypes]

Hidradenitis suppurativa (HS) is not an infectious disease; it is a debilitating, chronic autoinflammatory skin condition characterized by inflammation of the hair follicles. It presents in different phenotypes, ranging from recurrent abscesses and nodules to extensive tunnel- and scar formation. HS is associated with smoking, obesity, and various inflammatory and metabolic comorbidities. Both physical and psychological symptoms significantly affect the quality of life of patients. Treatments for this heterogeneous condition include anti-inflammatory medication and/or surgery. The refined Hurley classification, a three-step algorithm, helps determine the severity of HS and guide treatment choices. This article highlights three cases to illustrate the diverse manifestations of HS and emphasizes the importance of a multidisciplinary approach.