Related Experiment Video
Updated: Sep 13, 2025

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Grading retinal displacement after retinal detachment repair: a prospective study linking displacement grade and
Ofri Vorobichik Berar1,2, Gabriel Katz3,4, Miri Meira Fogel Levin3,4
1Goldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel. berar.ofri@gmail.com.
Background:
To evaluate the impact of surgical technique, preoperative findings, and the degree of retinal displacement on visual outcomes in patients undergoing repair for rhegmatogenous retinal detachment (RRD).
Methods:
In this prospective cohort study, all consecutive patients with RRD treated at Sheba Medical Center between March 2021 and March 2022 were included. Data on surgical techniques, visual acuity (VA), preoperative posterior vitreous detachment (PVD), and postoperative imaging were collected. Retinal displacement was graded based on fundus autofluorescence and correlated with visual outcomes.
Results:
A total of 128 eyes from 128 patients (mean age 56.7 ± 15.4 years) were analyzed. Pars plana vitrectomy (PPV) was the most common procedure (79.9%), followed by scleral buckle (SB, 18.8%) and pneumatic retinopexy (2.3%). Significant improvement in VA was observed across all surgical groups. Retinal displacement was more frequent following PPV (68%) compared to SB (16%). Higher displacement grades (2-3) were associated with significantly worse final VA (p = 0.024). The presence of preoperative PVD positively correlated with surgical success in the PPV group (p = 0.003). Early postoperative signs of displacement included retinal folds and photoreceptor changes.
Conclusions:
Preoperative PVD status is a significant predictor of surgical success in PPV-treated RRD. Grading of retinal displacement offers a practical tool to assess its functional impact, with higher grades correlating with worse visual outcomes. Identifying risk factors for visually significant displacement may improve surgical decision-making and patient prognosis.

