Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Autism Spectrum Disorder

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

Modeling in Therapy

Modeling in Therapy

Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

Epigenetic Regulation

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mixing Is Dispensable for Optical Density-Based High-Throughput Growth Screening Assay in Fission Yeast.

International journal of molecular sciences·2026

Same author

Set2 regulates Ccp1 and Swc2 to ensure centromeric stability by retargeting CENP-A.

Nucleic acids research·2024

Same author

A Normalization Protocol Reduces Edge Effect in High-Throughput Analyses of Hydroxyurea Hypersensitivity in Fission Yeast.

Biomedicines·2023

Same author

Resistance to Chemotherapeutic 5-Fluorouracil Conferred by Modulation of Heterochromatic Integrity through Ino80 Function in Fission Yeast.

International journal of molecular sciences·2023

Same author

Application of the fission yeast Schizosaccharomyces pombe in human nutrition.

FEMS yeast research·2022

Same author

GRANT Motif Regulates CENP-A Incorporation and Restricts RNA Polymerase II Accessibility at Centromere.

Genes·2022

Search research articles

Related Experiment Video

Updated: Sep 13, 2025

Strategies for Assessing Autistic-Like Behaviors in Mice

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Emerging Epigenetic Therapeutics and Diagnostics for Autism Spectrum Disorder.

Cassie Kao¹, Kim Kiat Lim¹, Ee Sin Chen^1,2,3,4,5

¹Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.

Current Issues in Molecular Biology

|July 29, 2025

Summary

Epigenetic factors are increasingly linked to autism spectrum disorder (ASD) pathogenesis. Understanding these epigenetic mechanisms may lead to early detection and personalized treatments for ASD.

Keywords:

ASD autism autism spectrum disorder epigenetic maternal immune activation methylation microbiome perinatal

More Related Videos

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

Related Experiment Videos

Last Updated: Sep 13, 2025

Strategies for Assessing Autistic-Like Behaviors in Mice

Strategies for Assessing Autistic-Like Behaviors in Mice

Published on: September 20, 2024

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs

Published on: March 2, 2018

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

Area of Science:

Neuroscience
Genetics
Developmental Biology

Background:

Autism spectrum disorder (ASD) affects approximately 1 in 100 children, characterized by social communication difficulties and repetitive behaviors.
Current management relies on occupational therapy and limited medical interventions, with no known cure.
The underlying causes of ASD are not fully understood, but epigenetic dysregulation is an emerging area of research.

Purpose of the Study:

To review recent findings on epigenetic regulatory pathways in ASD development.
To explore emerging therapeutics targeting epigenetic factors for ASD.
To discuss the implications for prevention, diagnosis, and personalized management of ASD.

Main Methods:

Literature review of recent studies on epigenetics and ASD.
Analysis of epigenetic regulatory pathways and factors implicated in ASD.
Synthesis of findings related to diagnostic and therapeutic strategies.

Main Results:

Epigenetic dysregulation plays a significant role in the pathogenesis of ASD.
Emerging research highlights novel epigenetic targets for ASD therapeutics.
Findings suggest potential for early, non-invasive diagnostic tests and personalized treatment approaches.

Conclusions:

Epigenetic insights offer new avenues for understanding and managing ASD.
Further research into epigenetic mechanisms can inform preventive strategies for mothers.
Personalized medicine approaches based on epigenetics hold promise for improved ASD outcomes.