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Complex Presentation of Lung Cancer with Obstructive Jaundice
Ruxandra Oprita1,2, Bogdan Oprita1,3, Ioana Adriana Serban2
1Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", 050474 Bucharest, Romania.
Reports (MDPI)
|July 29, 2025
Summary
A rare case of small-cell lung cancer (SCLC) presented with obstructive jaundice and abdominal pain due to metastasis. This highlights the importance of considering SCLC metastasis in patients with jaundice and lung cancer risk factors.
Area of Science:
- Oncology
- Gastroenterology
- Pulmonology
Background:
- Small-cell lung carcinoma (SCLC) typically presents with respiratory symptoms.
- Atypical presentations, such as jaundice and abdominal pain, can delay SCLC diagnosis.
Observation:
- A 49-year-old male with COPD and smoking history presented with jaundice and abdominal pain.
- Imaging revealed pancreatic and liver masses, initially suggesting pancreatic cancer.
- Biopsy confirmed duodenal metastasis from SCLC.
Findings:
- The patient was diagnosed with metastatic small-cell lung carcinoma presenting as obstructive jaundice.
- Immunohistochemistry confirmed the lung origin of the metastatic neuroendocrine tumor.
Implications:
- This case underscores the importance of considering metastatic SCLC in the differential diagnosis of obstructive jaundice, especially in patients with risk factors for lung cancer.
- Early recognition of atypical SCLC metastasis can improve patient outcomes.
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