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A Case of De Novo Positional Complex Sleep Apnea Syndrome (CompSAS)
Abdelkarim Khalifa1, Marc Spielmanns1,2
1Sleep Medicine Center Zurich Oberland, GZO Wetzikon, 8620 Wetzikon, Switzerland.
Reports (MDPI)
|July 29, 2025
Summary
Sleep position therapy can improve complex sleep apnea syndrome (CompSAS), particularly central sleep apnea (CSA) components. This case study highlights positional therapy
Area of Science:
- Sleep Medicine
- Respiratory Physiology
Background:
- Obstructive sleep apnea (OSA) often improves with non-supine positioning.
- Emerging evidence suggests sleep position management may also benefit central sleep apnea (CSA).
Observation:
- A 78-year-old female presented with syncope, diagnosed with moderate OSA via polysomnography (PSG).
- A de novo complex sleep apnea syndrome (CompSAS) developed during automatic positive airway pressure (APAP) therapy.
- Previous ASV and BiPAP-ST therapies showed limited benefit, though CSA reduced in non-supine positions.
Findings:
- Sleep positional therapy (SPT) significantly improved CSA and overall sleep quality.
- Non-supine positioning demonstrated a reduction in central sleep apnea events.
Implications:
- Positional therapy is a potential adjunctive treatment for CompSAS with positional CSA.
- Further research is warranted to determine the prevalence of positional CSA.
- Individualized sleep apnea management strategies may benefit from considering sleep position.
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