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A Multicenter Study of Factors Related to Early Implant Failures-Part 2: Patient Factors
Rachel Duhan Wåhlberg1,2,3, Victoria Franke Stenport1, Ann Wennerberg1
1Department of Prosthodontics/Dental Materials Science, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE, Sweden.
Clinical Implant Dentistry and Related Research
|July 29, 2025
Summary
Patient factors like food allergies and exposed implant threads are linked to early dental implant failure. Understanding these risks helps improve patient outcomes and implant success rates.
Area of Science:
- Dental Implantology
- Biomaterials Science
- Clinical Dentistry
Background:
- Dental implant technology has advanced, enabling treatment for patients with complex medical histories.
- Individualized risk assessment is crucial for successful dental implant procedures.
- Further research is needed to understand patient-specific factors influencing early dental implant failure.
Purpose of the Study:
- To investigate patient-related factors contributing to early dental implant complications and failures.
- To compare findings between two distinct patient cohorts treated in 2007 and 2017.
Main Methods:
- Analysis of a patient-level dataset from two cohorts (2007 and 2017) with consistent data collection.
- Univariate analysis to identify potential risk factors (p < 0.20).
- Multivariable logistic regression modeling to determine significant predictors of early implant failure and complications (p < 0.05).
Main Results:
- A total of 1875 patients and 4670 implants were analyzed.
- The 2017 cohort showed significantly more implant failures (2.4%) and early complications (13.5%) compared to the 2007 cohort (1.1% and 7.0%, respectively).
- Key factors associated with increased early failure risk included food allergy, exposed implant threads, and a higher number of implants. Factors linked to complications included smoking, exposed threads, no preoperative antibiotics, number of implants, sinus perforations, food allergy, and metal allergy.
Conclusions:
- Identified three patient-related factors significantly associated with early dental implant failure.
- Determined seven factors linked to an increased risk of early implant complications.
- Highlights the importance of considering patient-specific factors in dental implant treatment planning.

