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Updated: Sep 13, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Democratizing cost-effective, agentic artificial intelligence to multilingual medical summarization through knowledge
Chanseo Lee1,2, Sonu Kumar3, Kimon A Vogt3
1Sporo Health, Boston, MA, USA. chanseo.lee@yale.edu.
Abstract:
The increasing demand for multilingual capabilities in healthcare technology highlights the critical need for AI solutions capable of handling underrepresented languages, such as Arabic, in clinical documentation. Arabic's unique linguistic complexities-morphological richness, syntactic variations, and diglossia-present significant challenges for foundational large language models (LLMs), especially in domain-specific tasks like medical summarization. This study introduces AraSum, a domain-specific AI agent built using a novel knowledge distillation framework that transforms large multilingual LLMs into lightweight, task-optimized small language models (SLMs). Leveraging a synthetic dataset of Arabic medical dialogues, AraSum demonstrates superior performance over JAIS-30B, a foundational Arabic LLM, across key evaluation metrics, including BLEU and ROUGE scores. AraSum also outperforms JAIS in Arabic-speaking evaluator assessments of accuracy, comprehensiveness, and clinical utility while maintaining comparable linguistic performance as measured by a modified PDQI-9 inventory. Beyond accuracy, AraSum achieves these results with significantly lower computational and environmental costs, demonstrating the feasibility of deploying resource-efficient AI models in low-resource settings for domain-specific tasks. This work underscores the potential of SLM-based agentic architectures for advancing multilingual healthcare, encouraging sustainable artificial intelligence, and fostering equity in access to care.
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