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The leukocyte count in labor.

D B Acker, M P Johnson, B P Sachs

    American Journal of Obstetrics and Gynecology
    |December 1, 1985
    PubMed
    Summary
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    Leukocyte counts in laboring women increase with labor duration. Mild elevations can be managed expectantly, but significant increases warrant infection investigation.

    Area of Science:

    • Obstetrics and Gynecology
    • Hematology

    Background:

    • Leukocyte count is a common indicator of physiological stress and infection.
    • Understanding leukocyte count changes during labor is crucial for accurate clinical interpretation.

    Purpose of the Study:

    • To investigate the relationship between leukocyte count and labor duration in pregnant women.
    • To establish reference ranges for leukocyte counts during labor.

    Main Methods:

    • Leukocyte counts were measured in 479 laboring women.
    • Statistical analysis, including linear regression, was used to assess the relationship with labor duration.

    Main Results:

    • Leukocyte count showed a linear increase with the duration of labor (y = 0.2174x + 10.31, p < 0.001).

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  • Mild elevations may be considered normal, but increases exceeding 2 standard deviations suggest potential infection.

    • Conclusions:

    • Leukocyte count elevation during labor is often a normal physiological response correlated with labor duration.
    • Clinicians should consider labor duration when interpreting leukocyte counts and diligently search for infection in cases of significant elevation.