Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

4.4K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.4K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

40
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
40
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

207
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
207

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Alogliptin/Amentoflavone Combination Mitigates Bleomycin-Induced Lung Fibrosis: The Role of Oxidative Stress, TXNIP-Mediated Pyroptosis, and Autophagy/Apoptosis Balance.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Identification of Quinoline Tethered Thiadiazole/Thiazole Derivatives as Potent Tyrosinase Inhibitors With Promising Anti-Toxoplasma gondii Agents: Design, Synthesis, and Computational Analysis.

Drug development research·2026
Same author

Smoking and medication-overuse headache: Exploring the potential link between nicotine dependence and analgesic overuse.

Cephalalgia : an international journal of headache·2026
Same author

Evaluation of the Potential Anti-Inflammatory Effect of a New Coumarin-Quinoline Hybrid in LPS-Induced Neuroinflammation.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Terpene-Enriched Nitazoxanide-Loaded Chondrosomes: Aerodynamic Characterization and In Silico Evaluation of Antiviral Activity.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Arabic version of the General Sleep Disturbance Scale among healthcare night-shift workers: a cross-sectional validation study.

BMJ neurology open·2026

Related Experiment Video

Updated: Sep 13, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.0K

Microbial Multidrug-Resistant Organism (MDRO) Mapping of Intensive Care Unit Infections.

Ahmed Yassin1, Ragaey Ahmad Eid2, Mohammad Farouk Mohammad3

  • 1Department of Critical Care Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef 62514, Egypt.

Medicina (Kaunas, Lithuania)
|July 30, 2025
PubMed
Summary
This summary is machine-generated.

Multidrug-resistant organism (MDRO) infections in Egyptian ICUs are linked to higher mortality and complications. Prior antibiotic use and invasive devices are key risk factors, necessitating better antimicrobial stewardship.

Keywords:
MDROsantibioticscritically ill patientsinfectionsintensive care units

More Related Videos

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection
09:49

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection

Published on: November 18, 2022

2.2K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

6.8K

Related Experiment Videos

Last Updated: Sep 13, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

13.0K
Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection
09:49

Investigation of Microbial Cooperation via Imaging Mass Spectrometry Analysis of Bacterial Colonies Grown on Agar and in Tissue During Infection

Published on: November 18, 2022

2.2K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

6.8K

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Microbiology

Background:

  • Antimicrobial overuse drives multidrug-resistant organism (MDRO) infections, increasing morbidity, mortality, and costs in intensive care units (ICUs).
  • Understanding MDRO risk factors and outcomes is crucial for effective management in critical care settings.

Purpose of the Study:

  • To identify risk factors for multidrug-resistant organism (MDRO) infections in Egyptian ICUs.
  • To assess the impact of MDRO infections on patient outcomes, including mortality and complications.

Main Methods:

  • A 12-month prospective observational study involving 113 adult patients with bacterial infections in an ICU.
  • Data collection included medical assessments, multisource cultures, patient histories, and documentation of disease progression.
  • Patients were categorized into MDRO-infected and non-MDRO-infected groups for comparative analysis.

Main Results:

  • MDRO infections accounted for 42% of infections, with Klebsiella spp. being the most common (52%).
  • Patients with MDRO infections exhibited significantly higher mortality (42.6%), increased ARDS incidence, and longer ventilation durations.
  • Independent risk factors for MDRO infection included prior antibiotic use (OR: 3.2) and presence of invasive devices (OR: 2.7).

Conclusions:

  • Cerebrovascular stroke and renal failure are identified as risk factors for MDRO infections.
  • MDRO infections in ICUs are associated with adverse clinical outcomes and increased complications.
  • Enhanced antimicrobial stewardship and targeted prevention strategies are essential to combat MDROs in ICUs.