Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bio-inspired self-assembly of omega-3 fatty acids and peptides for responsive drug delivery.

International journal of pharmaceutics: X·2026
Same author

Modulating STAT3 pathway in breast cancer: Improved activity of T40214 aptamer by peptide-based nanofibers delivering.

International journal of biological macromolecules·2026
Same author

Structure-Guided Design of Temporin-Derived Peptides Reveals Potent Dual-Mechanism Inhibitors of SARS-CoV-2.

Journal of medicinal chemistry·2026
Same author

<i>In Vitro</i> Properties of WMRK-gH625, a Novel Hybrid Peptide against Multidrug-Resistant Pathogens.

ACS omega·2025
Same author

Probing Guanidino Pendant or Bridged Groups in Cyclic Antimicrobial Peptides Derived from Temporin L: A Strategy to Improve Efficacy against Gram-Negative Bacteria.

Journal of medicinal chemistry·2025
Same author

Synergistic Cancer Metabolic Therapy via Co-Delivery of 3-Bromopyruvate and Temozolomide with a Supramolecular Shuttle.

ACS applied materials & interfaces·2025

Related Experiment Video

Updated: Sep 13, 2025

Assembly and Operation of an Acoustofluidic Device for Enhanced Delivery of Molecular Compounds to Cells
07:16

Assembly and Operation of an Acoustofluidic Device for Enhanced Delivery of Molecular Compounds to Cells

Published on: January 21, 2021

3.1K

Boosting AMPs' Power: From Structural Engineering to Nanotechnology-Based Delivery.

Oluwasegun Eric Ajayi1, Rosa Bellavita2, Lorenzo Emiliano Imbò3

  • 1INTHERAPI Graduate School, Universite de Bourgogne, 21000 Dijon, France.

Molecules (Basel, Switzerland)
|July 30, 2025
PubMed
Summary
This summary is machine-generated.

Antimicrobial peptides (AMPs) offer a promising alternative to traditional antibiotics for fighting antimicrobial resistance (AMR). Advances in AMP technology are enhancing their effectiveness and paving the way for new therapeutic applications.

Keywords:
antimicrobial peptidesbiofilmsdrug deliverynanoparticle conjugationpeptide strategies

More Related Videos

Optimization, Test and Diagnostics of Miniaturized Hall Thrusters
12:22

Optimization, Test and Diagnostics of Miniaturized Hall Thrusters

Published on: February 16, 2019

9.1K
Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

12.5K

Related Experiment Videos

Last Updated: Sep 13, 2025

Assembly and Operation of an Acoustofluidic Device for Enhanced Delivery of Molecular Compounds to Cells
07:16

Assembly and Operation of an Acoustofluidic Device for Enhanced Delivery of Molecular Compounds to Cells

Published on: January 21, 2021

3.1K
Optimization, Test and Diagnostics of Miniaturized Hall Thrusters
12:22

Optimization, Test and Diagnostics of Miniaturized Hall Thrusters

Published on: February 16, 2019

9.1K
Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

12.5K

Area of Science:

  • Biochemistry
  • Pharmacology
  • Molecular Biology

Background:

  • Antimicrobial resistance (AMR) is a growing global health threat.
  • Conventional antibiotics face challenges in combating resistant pathogens.
  • Antimicrobial peptides (AMPs) show potential as adjuncts or alternatives to antibiotics.

Purpose of the Study:

  • To review the role of AMPs in addressing AMR.
  • To explore the therapeutic potential and challenges of AMPs.
  • To highlight recent advances in AMP development and application.

Main Methods:

  • Literature review of recent research on AMPs.
  • Analysis of AMP mechanisms of action and applications.
  • Evaluation of strategies to overcome AMP limitations.

Main Results:

  • AMPs possess broad-spectrum activity and unique mechanisms against pathogens.
  • Potential applications include combating multidrug-resistant organisms, immune modulation, and cancer therapy.
  • Challenges like toxicity, instability, and cost are being addressed through design and delivery innovations.

Conclusions:

  • Advances in AMP design, optimization, and delivery enhance efficacy and specificity.
  • Integration into precision medicine and combination therapies can overcome limitations.
  • AMPs hold significant potential to transform infection management and other medical fields.