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Updated: Sep 13, 2025

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Short Assessment for People with Human Immunodeficiency Virus (HIV) Aged 50 Years or Older: Essential Tests from

Jordi Puig1,2,3, Pau Satorra4, Ana Martínez1

  • 1Fundació Lluita Contra Les Infeccions, Department of Infectious Diseases, Hospital Universitari Germans Trias i Pujol, Germans Trias i Pujol, 08916 Badalona, Spain.

Viruses
|July 30, 2025
PubMed

Insights

A short comprehensive geriatric assessment (CGA) effectively identifies older adults with human immunodeficiency virus (HIV) who need clinical management. This streamlined approach aids in early intervention for this growing population.

Area of Science:

  • Gerontology
  • Infectious Diseases
  • Public Health

Background:

  • Comprehensive geriatric assessments (CGAs) are crucial for older adults with human immunodeficiency virus (PWH) aged ≥ 50 years.
  • Ensuring high-quality care for PWH requires addressing their unique geriatric needs.
  • Existing CGAs are extensive, necessitating a more streamlined approach.

Purpose of the Study:

  • To identify the most effective tests within a comprehensive CGA.
  • To develop a shorter, more efficient CGA for PWH aged ≥ 50.
  • To facilitate early clinical management for PWH.

Main Methods:

  • An observational, cross-sectional, and analytical study in three phases.
  • Phase 1: Described PWH aged ≥ 50 and matched controls.
  • Phase 2: Identified effective tests for a short CGA; Phase 3: Applied the short CGA to both groups.

Main Results:

  • A short CGA using the Lawton scale, SPPB, Barber questionnaire, Pittsburgh Sleep Quality Index, and Cognitive Complaints questionnaire was developed.
  • The short CGA identified abnormalities in 77% of PWH flagged by the full CGA.
  • 65% of individuals with normal short CGA results had abnormalities in the full version, with Hearing-Dependent Activities scale exclusions noted as a factor.

Conclusions:

  • The developed short CGA is an initial step toward easy and rapid identification of PWH aged ≥ 50.
  • This tool can help identify individuals who may benefit from early clinical management.
  • The short CGA extends beyond frailty assessment to capture broader geriatric needs in PWH.

Keywords:
HIVagingearly managementgeriatric assessmentgeriatric syndromespsychosocial factors

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