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Related Concept Videos

Vaccinations01:51

Vaccinations

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Overview
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Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

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Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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Introduction to Virus01:28

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Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
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Vaccine Production01:23

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Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
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Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

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Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
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Vaccines01:21

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Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
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Vaccines and Vaccination: Feature Papers.

Pedro Plans-Rubió1

  • 1College of Physicians of Barcelona, 08017 Barcelona, Spain.

Vaccines
|July 30, 2025
PubMed
Summary

This Special Issue on Vaccines and Vaccination features research on increasing vaccine coverage. It explores various interventions and challenges in global immunization programs.

Area of Science:

  • Immunology and Public Health: Focuses on vaccine development and public health strategies.
  • Epidemiology: Examines disease patterns and the impact of vaccination on population health.

Background:

  • This Special Issue compiles research on vaccines and vaccination.
  • Articles cover diverse topics, including interventions to improve vaccination rates.

Discussion:

  • Addresses challenges and opportunities in vaccine implementation.
  • Highlights the importance of vaccination in preventing infectious diseases.

Key Insights:

  • Interventions can significantly boost vaccination coverage.
  • Multifaceted approaches are crucial for successful immunization programs.

Outlook:

  • Future research should focus on novel vaccine technologies.

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  • Sustained efforts are needed to achieve global vaccination equity.