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Updated: Sep 13, 2025

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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CDR1as modulates arrhythmia post-myocardial infarction via regulating Cav1.2

Jiapan Wang1, Wenjie Liao1, Xingda Li1

  • 1Institute of Clinical Pharmacy of the Second Affiliated Hospital of Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin 150001, China.

Acta Biochimica Et Biophysica Sinica
|July 30, 2025
PubMed
Summary

Targeting CDR1as may prevent heart arrhythmias after myocardial infarction (MI). Reducing CDR1as expression restored calcium channel function and improved cardiac performance in mouse models of MI.

Keywords:
CDR1asCav1.2myocardial infarctionventricular arrhythmia

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